Visual Legend

Entity

Visual Shape

Physical Entities, such as proteins, small molecules, complexes, etc. Ellipse Shape
Interaction Entities, such as biochemical reactions, catalysis, etc. Square Shape

Edge Type

Arrow Shape

Inhibition Black inhibition arrow type
Containment, e.g. a complex can contain one or more proteins. Black ciricle arrow type
All other edge types, e.g. activation, left, right, etc. Black arrow type

Labels for Physical Entities

All physical entities will be labeled as follows:
[NAME] [-CHEMICAL MODIFICATION ABBR] [(CELLULAR LOCATION ABBR)]
where [CHEMICAL MODIFICATION ABBR] and [CELLULAR LOCATION ABBR] are one of the abbreviations described below.

Examples

MITF MITF
MITF Phosphorylated MITF-P
MITF Phosphorylated, in the cytoplasm MITF-P (CP)

Abbreviations for Chemical Modifications

acetylated A
glycosylated G
phosphorylated P
proteolytic cleavage PCS
sumoylated S
ubiquitinated U
[All others] No Abbreviation provided

Abbreviations for Cellular Locations

centrosome CE
cytoplasm CY
endoplasmic reticulum ER
endosome EN
extracellular matrix EM
golgi apparatus GA
mitochondrion MI
nucleoplasm NP
nucleus NU
plasma membrane PM
ribosome RI
transmembrane TM
[All others] No Abbreviation provided